Acute Lymphoblastic Leukemia Annotated Bibliography

Acute Lymphoblastic Leukemia - Annotated Bibliography Example The researcher of this essay aims to analyze and discuss studies, that were conducted by the researchers on the subject of Acute Lymphoblastic Leukemia disease, that is a cancer that mainly attacks the bone marrow and arises from cancerous and immature white blood cells called lymphoblast. The two subtypes of lymphocytes are T and B cells. The authors of the studies, that were discussed stipulate that 80% of acute lymphoblastic leukemia arise from immature B-lymphocytes. The disease is most prevalent in children; nevertheless, it has also increased in elderly populace mostly of ages 60 years and over. The main symptoms of acute lymphoblastic leukemia are buildup of the abnormal and immature white blood cells within the bone marrow and blood. Blast cells collect out of the normal cells within the bone marrow thus lowering blood counts. The disease results to decrease in normal white cells making an individual to be susceptible to infection such as sinuses, bronchitis, and pneumonia. T he main signs are; enlargement of the lymph nodes within the neck and arms coupled with enlargement of the spleen. This journal also describes the treatment options for acute lymphoblastic leukemia. Acute lymphoblastic leukemia is treated by multiple chemotherapy drugs via mouth or via special intravenous line that is normally placed within a vein in the arm or chest and maintain for several months. According to Knowles, the chromosomes that lead to the development of Acute Lymphoblastic leukemia is sill not known today.